High-Protein Pepperoni Stromboli

Featured in: Comfort Food Favorites

This hearty stromboli delivers 26g of protein per serving by combining lean ground beef, pepperoni, and two types of cheese in a crispy pizza dough roll. Seasoned with oregano and garlic, then baked until golden brown, it's an Italian-American comfort food that works perfectly as a main dish or satisfying snack. Ready in under an hour with simple ingredients.

Updated on Sun, 01 Feb 2026 10:20:00 GMT
Freshly baked Baked High-Protein Pepperoni Stromboli slices with melted mozzarella and golden crust are served warm with a small bowl of marinara sauce for dipping. Save It
Freshly baked Baked High-Protein Pepperoni Stromboli slices with melted mozzarella and golden crust are served warm with a small bowl of marinara sauce for dipping. | zetluna.com

One winter evening, I was craving something warm and filling but didn't want to wait an hour for delivery. I had pizza dough in the fridge, ground beef thawing, and a pack of pepperoni that had been sitting there since game day. Rolling everything into one golden, crispy package felt like cheating in the best way. When I pulled that first stromboli out of the oven, the smell alone had my roommate wandering into the kitchen asking what I ordered.

I made this for a potluck once, and it disappeared faster than anything else on the table. People kept asking if I'd ordered it from somewhere, which honestly made me feel like a kitchen genius. The crispy crust, gooey cheese, and savory filling hit every comfort food note. I've been making it ever since whenever I need to feed a crowd or just want something that feels like a hug in food form.

Ingredients

  • Refrigerated pizza dough: This is your foundation, so let it sit at room temperature for 10 minutes before rolling to avoid tearing.
  • Lean ground beef: Browning it with spices first adds deep flavor and keeps the filling from being watery.
  • Mozzarella and Parmesan cheese: The mozzarella melts beautifully while Parmesan adds a sharp, salty kick that balances the richness.
  • Sliced pepperoni: It crisps up slightly in the oven and brings that classic pizza taste everyone loves.
  • Pizza sauce: A thin layer inside keeps things moist, and extra on the side makes dipping irresistible.
  • Beaten egg and olive oil: Brushing this on top gives you that golden, bakery-style shine and crispness.

Instructions

Product image
Grill meats and vegetables indoors with beautiful sear marks and easy cleanup using minimal oil.
Check price on Amazon
Prep Your Oven and Pan:
Preheat to 400°F and line a baking sheet with parchment paper. This prevents sticking and makes cleanup a breeze.
Cook the Beef:
Brown the ground beef with salt, pepper, oregano, and garlic powder over medium heat until fully cooked, then drain the fat. Let it cool slightly so it doesn't melt the cheese too early.
Roll Out the Dough:
On a floured surface, roll the pizza dough into a large rectangle, about 12x16 inches. Aim for even thickness so it bakes uniformly.
Spread the Sauce:
Spread pizza sauce evenly over the dough, leaving a 1-inch border. This border helps you seal the edges without sauce oozing out.
Layer the Filling:
Evenly distribute the cooked beef, mozzarella, Parmesan, and pepperoni over the sauce. Don't overstuff or it'll be hard to roll.
Roll It Up:
Starting from one long edge, tightly roll the dough into a log, then pinch the seam and ends to seal. A tight roll keeps everything inside while baking.
Transfer and Brush:
Place the stromboli seam side down on the baking sheet, then brush the top with beaten egg and drizzle with olive oil. This creates that gorgeous golden crust.
Vent and Bake:
Make several diagonal slits on top with a sharp knife to let steam escape, then bake for 25 to 30 minutes until golden brown. The slits prevent it from bursting open.
Rest and Slice:
Let it cool for 5 to 10 minutes before slicing so the cheese sets slightly. Garnish with parsley if you like and serve warm with extra pizza sauce.
Product image
Grill meats and vegetables indoors with beautiful sear marks and easy cleanup using minimal oil.
Check price on Amazon
Golden-baked Baked High-Protein Pepperoni Stromboli reveals savory ground beef and pepperoni filling inside fluffy pizza dough on a rustic wooden cutting board. Save It
Golden-baked Baked High-Protein Pepperoni Stromboli reveals savory ground beef and pepperoni filling inside fluffy pizza dough on a rustic wooden cutting board. | zetluna.com

The first time I served this to my family, my dad asked for the recipe before he even finished his first slice. It became our go-to for Sunday dinners and movie nights. There's something about breaking into that crispy crust and pulling out gooey, savory filling that just brings people together.

Storing and Reheating

Wrap leftover slices tightly in foil and refrigerate for up to three days. Reheat in a 350°F oven for about 10 minutes to restore that crispy crust, or microwave for a quick fix, though it won't be as crunchy. I've also frozen baked stromboli, wrapped well, for up to a month and it reheats beautifully straight from the freezer.

Customizing Your Stromboli

You can swap the ground beef for turkey or chicken if you want it leaner, or even go vegetarian with sautéed mushrooms and spinach. Adding diced bell peppers or onions to the filling brings extra flavor and a little sweetness. I've tried it with different cheeses like provolone or fontina, and each version brings its own character.

Serving Suggestions

This stromboli is hearty enough to be a full meal, but it pairs wonderfully with a simple green salad or roasted veggies on the side. A bowl of marinara or garlic butter for dipping takes it over the top. It also makes a fantastic party appetizer when sliced into smaller rounds.

  • Serve with a crisp Caesar salad for a balanced plate.
  • Pair with a cold beer or sparkling water with lemon.
  • Slice into bite-sized pieces for game day snacking.
Product image
Boil water quickly for tea, coffee, instant soups, and faster prep when cooking grains or noodles.
Check price on Amazon
Freshly sliced Baked High-Protein Pepperoni Stromboli showcases cheesy mozzarella strands and pepperoni layers on a parchment-lined tray for a hearty family dinner. Save It
Freshly sliced Baked High-Protein Pepperoni Stromboli showcases cheesy mozzarella strands and pepperoni layers on a parchment-lined tray for a hearty family dinner. | zetluna.com

Whether you're feeding a hungry crowd or just want something comforting and delicious, this stromboli delivers every time. It's become one of those recipes I turn to when I want to feel like I really cooked, without spending all evening in the kitchen.

Common Questions About Recipes

Can I prepare stromboli ahead of time?

Yes, you can assemble the stromboli up to 24 hours in advance. Wrap it tightly in plastic wrap and refrigerate. Brush with egg wash just before baking, and add 5-10 minutes to the cooking time if baking straight from the refrigerator.

How do I prevent the filling from leaking out?

Make sure to leave a 1-inch border when adding filling, and pinch the seam and ends firmly to seal. The diagonal slits on top allow steam to escape, preventing pressure buildup that could cause leaks. Let it rest 5-10 minutes before slicing.

What can I substitute for ground beef?

Ground turkey or chicken work excellently for a leaner option. You can also use Italian sausage for more flavor, or try plant-based ground meat alternatives for a vegetarian version. Just ensure any meat is fully cooked before assembling.

How should I store leftover stromboli?

Store leftovers in an airtight container in the refrigerator for up to 3 days. Reheat slices in a 350°F oven for 10-12 minutes to restore crispness, or microwave for 1-2 minutes for a quicker option. It also freezes well for up to 2 months.

Can I add vegetables to this stromboli?

Absolutely! Sautéed bell peppers, onions, mushrooms, or spinach make excellent additions. Just cook them first to remove excess moisture, which helps prevent a soggy crust. Layer them with the meat and cheese for balanced flavor.

Why brush the stromboli with egg and oil?

The beaten egg creates a beautiful golden-brown finish and helps seal the dough, while the olive oil adds extra crispness and shine to the crust. This combination gives you that professional bakery appearance and texture.

High-Protein Pepperoni Stromboli

Protein-packed stromboli with lean beef, pepperoni, and gooey mozzarella wrapped in golden pizza dough.

Prep Time
25 mins
Time to Cook
30 mins
Overall Time
55 mins
Authored by Clara


Skill Level Required Medium

Cuisine Type Italian-American

Recipe Output 6 Number of Portions

Dietary Needs None specified

The Ingredients You'll Need

Dough

01 1 pound refrigerated pizza dough

Filling

01 1/2 pound lean ground beef
02 1/2 teaspoon salt
03 1/2 teaspoon black pepper
04 1/2 teaspoon dried oregano
05 1/2 teaspoon garlic powder
06 1 cup shredded mozzarella cheese
07 1/2 cup grated Parmesan cheese
08 3 ounces sliced pepperoni
09 1/4 cup pizza sauce, plus extra for serving
10 1 tablespoon chopped fresh parsley, optional

For Brushing

01 1 egg, beaten
02 1 tablespoon olive oil

Step-by-Step Instructions

Step 01

Preheat and Prepare: Preheat oven to 400°F. Line a baking sheet with parchment paper.

Step 02

Brown the Meat: In a skillet over medium heat, cook ground beef with salt, pepper, oregano, and garlic powder until fully browned. Drain excess fat and let cool slightly.

Step 03

Roll Out Dough: On a floured surface, roll out pizza dough into a large rectangle approximately 12 by 16 inches.

Step 04

Apply Sauce Base: Spread pizza sauce evenly over dough, leaving a 1-inch border along all edges.

Step 05

Layer Fillings: Evenly distribute cooked beef, mozzarella, Parmesan, and pepperoni over sauce in successive layers.

Step 06

Roll and Seal: Starting from one long edge, tightly roll dough into a log, pinching seam and ends to seal completely.

Step 07

Transfer to Baking Sheet: Place stromboli on prepared baking sheet with seam side down.

Step 08

Brush and Score: Brush top with beaten egg and drizzle with olive oil. Using a sharp knife, make several diagonal slits across top to vent steam.

Step 09

Bake: Bake for 25 to 30 minutes until golden brown and cooked through.

Step 10

Rest and Serve: Cool for 5 to 10 minutes before slicing. Garnish with parsley if desired. Serve warm with extra pizza sauce for dipping.

Tools You'll Need

  • Skillet
  • Baking sheet
  • Parchment paper
  • Rolling pin
  • Sharp knife
  • Pastry brush

Allergy Information

Review each ingredient to identify allergens and consult an expert if needed.
  • Contains wheat and gluten
  • Contains milk and dairy products
  • Contains eggs
  • Pepperoni may contain soy and other allergens—verify labels if sensitive

Nutritional Facts (Per Serving)

Keep in mind these details are for general guidance and shouldn't replace professional advice.
  • Caloric Content: 410
  • Fats: 22 grams
  • Carbohydrates: 29 grams
  • Proteins: 26 grams