01 - Preheat oven to 350°F (175°C). Line a 12-cup muffin pan with paper liners or coat with non-stick spray.
02 - In a medium mixing bowl, whisk together all-purpose flour, baking powder, baking soda, salt, cinnamon, nutmeg, cloves, and ginger.
03 - In a large mixing bowl, thoroughly whisk pumpkin puree, vegetable oil, eggs, granulated sugar, brown sugar, and vanilla extract until the mixture is smooth.
04 - Gently fold the dry ingredients into the wet mixture just until combined. Take care not to overmix for optimal texture.
05 - Portion the batter evenly among the prepared muffin cups, filling each about two-thirds full. Place a heaping teaspoon of marshmallow creme on top of each portion, then swirl gently into the batter using a toothpick or skewer.
06 - Bake for 20 to 22 minutes, or until a toothpick inserted into the muffin portion (avoiding the marshmallow) emerges clean.
07 - Allow muffins to cool in the pan for 5 minutes. Transfer to a wire rack to cool completely before serving.